Type IV allergy

Potential sensitisation to metals, dental substances, or medications caused by an underlying mechanism of specific T cell activation and proliferation and results in a symptomatic type IV allergy (delayed hypersensitivity reaction) upon repeated contact with the material can be investigated using the 3HT Memory Spot, and in vitro test based on the lymphocyte transformation test (LTT) principle. The use of the standardised 3HT Memory Spot for diagnosing sensitisation to contact allergens is a valid alternative to an allergy patch test with regard to specificity and sensitivity. Compared to patch tests, the 3HT Memory Spot can also achieve detailed investigation of symptoms that do not occur on the skin, but instead appear in other organs or as a non-specific mood disorder. 3HT Memory Spot can also investigate sensitisation to allergens that occurs via non-cutaneous contact (dental substances, medications).