Vaginal microbiota

The vaginal flora of women of childbearing age is dominated by different types of lactobacilli in its physiological state. Due to the production of lactic acid, these lactobacilli provide an acidic environment with a pH value of < 4.5. An important physiological factor is the production of H2O2 by these bacteria. Changes in the flora caused by hormonal disorders or external factors, such as antibiotics or inadequate intimate hygiene often lead to imbalanced bacterial colonisation and to a reduction in its protective function. This results in colonisation or infections caused by pathogenic microorganisms. Symptoms range from short-term mucosal irritations to chronic and painful inflammations caused by bacterial vaginosis. Vaginal mycoses and colonisation with pathogenic streptococci can also occur. These are also favourable conditions for sexually transmitted diseases.

Our laboratory offers state-of-the-art Next Generation Sequencing for the analysis of both microbiota. The analysis is performed using a stool sample or vaginal smear. This analysis serves to determine the biodiversity, possible dysbiosis and individual risk profiles. These new analyses can be recommended for risk assessment in acute or recurrent complaints as well as in symptom-free conditions.